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HelpTest Code AFP Alpha-Fetoprotein (AFP) Tumor Marker, Serum
Additional Codes
| Mayo Test ID | COPIA Test Code | EPIC Test Codes | |
|---|---|---|---|
| AFP | AFP-Alpha-Fetoprotein, TM | LAB0232322 | ALPHA FETO PROTEIN - TUMOR MARKER |
Reporting Name
Alpha-Fetoprotein, Tumor Marker, SUseful For
Follow-up management of patients undergoing cancer therapy, especially for testicular and ovarian tumors and for hepatocellular carcinoma
Often used in conjunction with human chorionic gonadotropin.(2)
This test is not recommended as a screening procedure for cancer detection in the general population.
This test is not intended for the detection of neural tube defects.
This test is not useful for patients with pure seminoma or dysgerminoma.
Method Name
Immunoenzymatic Assay
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumOrdering Guidance
This test is used as a tumor marker and is not intended for the detection of neural tube defects. For testing amniotic fluid specimens, order AFPA / Alpha-Fetoprotein, Amniotic Fluid.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.6 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | |
| Frozen | 90 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
Special Instructions
Reference Values
<8.4 ng/mL
Reference values are for nonpregnant subjects only; fetal production of alpha-fetoprotein elevates values in pregnant women.
Range for newborns is not available, but concentrations over 100,000 ng/mL have been reported in normal newborns, and the values rapidly decline in the first 6 months of life.(See literature reference: Ped Res 1981;15:50-52) For further interpretive information, see Alpha-Fetoprotein (AFP)
Serum markers are not specific for malignancy, and values may vary by method.
Day(s) Performed
Monday through Friday
CPT Code Information
82105
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| AFP | Alpha-Fetoprotein, Tumor Marker, S | 53962-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| AFP | Alpha-Fetoprotein, Tumor Marker, S | 53962-7 |
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.Report Available
1 to 3 daysForms
If not ordering electronically, complete, print, and send Oncology Test Request (T729) with the specimen.