Test Code THSIF Thrombospondin Type 1 Domain Containing 7A (THSD7A), Immunofluorescence
Ordering Guidance
If additional interpretation/analysis is needed, request PATHC / Pathology Consultation along with this test and send the corresponding renal pathology light microscopy and immunofluorescence (IF) slides (or IF images on a CD), electron microscopy images (prints or CD), and the pathology report.
Necessary Information
A preliminary pathology report is required for testing to be performed. Send information with specimen. The laboratory will not reject testing if a reason for testing is not provided; however appropriate testing and interpretation may be compromised or delayed. If not provided, an appropriate indication for testing may be entered by Mayo Clinic Laboratories.
Specimen Required
Specimen Type: Kidney tissue
Preferred: 2 Unstained positively charged glass slide (25- x 75- x 1-mm) per test ordered; paraffin sections 3 to 4-microns thick
Acceptable: Formalin-fixed, paraffin-embedded (FFPE) kidney tissue block
Additional Information: Broken or cracked unstained slides will be rejected. Stained slides that were broken and repaired (ie, double mounted) at the client site will not be rejected, as, in most cases, they can still be reviewed under the microscope. However, due to the double mounting, digital scanning cannot be performed.
Useful For
Diagnosis of thrombospondin type 1 domain-containing 7A (THSD7A)-associated membranous nephropathy
Method Name
Direct Immunofluorescence (DIF)
Reporting Name
THSD7A ImmunofluorescenceSpecimen Type
SpecialSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Special | Ambient (preferred) | |
| Frozen | ||
| Refrigerated | ||
Reject Due To
Broken or cracked unstained slides are not compatible with the instrumentation used in our performing laboratories and will be rejected. Additional material may be requested. Attempts will be made to repair broken or cracked stained slides; however, if they are unable to be repaired (ie, shattered in transit), they will be rejected and discarded due to safety concerns.Performing Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
88346-Primary IF
88350-If additional IF
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| THSIF | THSD7A Immunofluorescence | 101116-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 605245 | Interpretation | 50595-8 |
| 606383 | Participated in the Interpretation | No LOINC Needed |
| 606384 | Report electronically signed by | 19139-5 |
| 606385 | Addendum | 35265-8 |
| 606386 | Gross Description | 22634-0 |
| 606387 | Material Received | 22633-2 |
| 606388 | Disclaimer | 62364-5 |
| 606389 | Case Number | 80398-1 |
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-Kidney Transplant Test Request
-Renal Diagnostics Test Request (T830)
Specimen Minimum Volume
See Specimen Required
Day(s) Performed
Monday through Friday