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Test Code XHIM X-Linked Hyper IgM Syndrome, Blood

Reporting Name

X-Linked Hyper IgM Syndrome, B

Useful For

Screening for X-linked hyper-IgM (XL-HIGM) or CD40L deficiency, primarily in male patients younger than 10 years

 

Ascertaining XL-HIGM carrier status in women of child-bearing age (younger than 45 years)

Method Name

Flow Cytometry

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

WB Sodium Heparin


Shipping Instructions


Testing is not performed on Saturday, Sunday, or observed holidays. Only collect and ship specimens for arrival on days when testing is performed.

 

Specimens received on days when testing is not performed or after 5 p.m. Central on Friday will be canceled if specimen is outside of stability when testing is next performed.

 

Collect and package specimen as close to shipping time as possible. It is recommended that specimens arrive within 24 hours of collection.



Necessary Information


The ordering healthcare professional's name and phone number are required.



Specimen Required


Container/Tube: Green top (sodium heparin)

Specimen Volume: 4 mL

Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.

Additional Information: For serial monitoring, it is recommended that specimen collection be performed at the same time of day.


Specimen Minimum Volume

1.2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
WB Sodium Heparin Ambient 72 hours GREEN TOP/HEP

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject

Reference Values

Present

Day(s) Performed

Monday through Friday

CPT Code Information

88184-Flow cytometry, cell surface, cytoplasmic

88185 x 6-Each additional marker

LOINC Code Information

Test ID Test Order Name Order LOINC Value
XHIM X-Linked Hyper IgM Syndrome, B 98239-7

 

Result ID Test Result Name Result LOINC Value
82964 CD40 Ligand Expression 98240-5
29040 CD40muIg (Function) 98241-3
23901 Interpretation 69052-9

Test Classification

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

Report Available

3 to 4 days